Patrocinadores de la SETGyC

Plata

AMGEN

Amgen discovers, develops, manufactures, and delivers innovative human therapeutics. A biotechnology pioneer since 1980, Amgen was one of the first companies to realize the new science’s promise by bringing safe, effective medicines from lab to manufacturing plant to patient. Amgen therapeutics have changed the practice of medicine, helping millions of people around the world in the fight against cancer, kidney disease, rheumatoid arthritis, bone disease, and other serious illnesses. With a deep and broad pipeline of potential new medicines, Amgen remains committed to advancing science to dramatically improve people’s lives.

Eurofancolen

Fanconi anemia (FA) is a rare inherited syndrome characterized by the early development of bone marrow failure and increasing predisposition to cancer with age. Allogeneic hematopoietic cell transplantation (alloHCT) is the only curative therapy for hematopoietic manifestations of FA, although associated with complications arising from myeloablation, graft versus host disease and increased incidence of squamous cell carcinoma. The genetic correction of autologous hematopoietic stem cells (HSC) with lentiviral vectors constitutes a recent and safe alternative for the treatment of different genetic diseases affecting mature cells from different tissues and/or committed progenitors of the hematopoietic system. One of the key features of FA that make it a unique disease for gene therapy approaches rely on the characteristic proliferation defect that is already evident in the very primitive HSCs. Thus, a marked survival advantage would be expected from corrected HSCs, potentially allowing normalization of hematopoiesis in the absence or after mild conditioning. Difficulties in the collection of sufficient numbers of HSC from FA patients and the use of sub-optimal transduction protocols with gammaretroviral vectors limited the success of FA gene therapy trials conducted 10 years ago in the USA. EuroFancoLen innovative approach is to develop for the first time an efficient and safe gene therapy of FA based on two recent innovations: 1) Discovery of potent HSC mobilizers, such as plerixafor Ans 2) Development of a new lentiviral vector by members of this Consortium, designed as Orphan Drug by the Europan Commission in December 2010: The main objective of this project is, therefore, the development of a multicentric Phase I/II gene therapy trial for FA-A patients, based on the genetic correction of plerixafor+G-CSF mobilized HSCs with the novel lentiviral vector, accompanied by comprehensive and groundbreaking safety and efficacy patient monitoring estudies.

TERCEL

The Spanish cell therapy network (TerCel) is a collaborative research project organized by the Spanish National Institute of Health Carlos III that started in 2003, to promote research in cell therapy and translate the scientific advances in this field to the clinic. Based on a multidisciplinary approach and the interaction and cooperation between 33 groups of basic and clinical scientists across Spain, the main objective of TerCel is to develop new medical therapies based on the use of stem cells for cardiovascular diseases, neurodegenerative diseases and osteo-articular, immune-hematologic and metabolic diseases. www.red-tercel.com

Ciberer

Rare diseases, affecting around 3 million Spanish people, are a social and health problem of the first order. The Centre for Biomedical Network Research on Rare Diseases (CIBERER), a network structure set up at the initiative of the Instituto de Salud Carlos III, pools and furthers the excellence research done in this country with the aim of finding diagnoses and therapies for those affected as quickly as possible.

uniQure

uniQure is delivering on the promise of gene therapy – single treatments with potentially curative results. We are leveraging our modular and validated technology platform to rapidly advance a pipeline of proprietary and partnered gene therapies to treat patients with CNS, liver/metabolic and cardiovascular diseases

Ciberned

CIBERNED is the acronym for "Centro de Investigación Biomédica En Red sobre enfermedades NEuroDegenerativas", a consortium that includes about 60 of the most competitive Spanish groups working on the molecular bases of neurodegenerative diseases. Group leaders are from universities, Spanish Research Council (CSIC) or hospitals from all over Spain, although most of the CIBERNED membres are based on Madrid or Barcelona. Research done by CIBERNED groups has a strong "translational" orientation. Therefore, besides research on pathogenesis and molecular bases of diseases (particularly Alzheimer's and Parkinson's diseases) many of these groups have also a strong focus on the development of new cell and gene therapies. CIBERNED is mainly supported by the Spanish Ministries of Health and Research through the Instituto de Salud Carlos III (Spanish Medical Research Council). 

VCN

VCN Biosciences is a privately-owned company focused in the development of new therapeutic approaches for tumors that lack effective treatment. The company uses oncolytic adenovirus technology platform to design highly selective and efficient agents that replicate and self-amplify exclusively in tumor cells. The selectivity of VCN oncolytic adenoviruses allows their systemic administration, which is especially relevant for the treatment of disseminated cancer. Contrary to chemotherapy, the ability of oncolytic virus to self-amplify in tumor cells results in an effective dose increase with time. These properties highlight VCN candidates as promising alternatives for the treatment of refractory tumors such as pancreatic adenocarcinomas, which is the current tumor target for its most advanced candidate, VCN-01.

Praxis

Praxis Group was founded in 2006 with the aim of offering a solution for the world of pain. This goal was pursued applying the most innovative advances in health science, developing solutions for rare and neglected diseases and regenerative medicine, aiming to improve life quality and patients’ social integration. 

Praxis Pharmaceutical is a company based in Miñano Technological Park, Álava, which operates in Europe and Latin America. The main purpose is to develop, manufacture and market high value added medicines, such as biotechnological sterile lyophilized drugs or micro/nano-metric based solutions.

Praxis is also pioneering cell-based therapy under GMP conditions.

In addition, the R&D team designs highly specialised formulations, such as:

  • Micro- and nanoformulations of innovative medicines
  • Innovative and sustainable solutions for the development and up scaling of pharmaceuticals
  • Advance Therapies for skin regeneration and proof of concept and implementation of genomic editing tools.

vivebiotech

VIVEBIOTECH S.L. es una spin-off promovida por Fundación Inbiomed para dar salida al mercado a los conocimientos acumulados relativos a las tecnologías de transferencia génica.

La misión de VIVEBIOTECH S.L. es fabricar productos de terapia génica para ensayos clínicos en humanos en riguroso cumplimiento de los requisitos establecidos en la legislación vigente y siguiendo las directrices de las Normas de Correcta Fabricación (GMP).

Además VIVEBIOTECH S.L. produce vectores virales derivados de lentivirus, de adenovirus y adeno-asociados (UNE-EN ISO 9001:2008) dando servicio a investigadores de la academia y la industria para estudios en investigación in vitro in vivo.

Celgene

Celgene is a global biopharmaceutical company committed to improving the lives of patients with certain types of cancer and other rare incurable diseases.

Our mission is to deliver truly innovative and life-changing drugs for our patients. As a company we work to build a major global biopharmaceutical corporation while focusing on the discovery, the development, and the commercialization of products for the treatment of cancer and other severe, immune, inflammatory conditions.

There are more than 300 clinical trials at major medical centers using compounds from Celgene. Investigational compounds are being studied for patients with incurable hematological and solid tumor cancers, including multiple myeloma, myelodysplastic syndromes, chronic lymphocyte leukemia (CLL), non-Hodgkin's lymphoma (NHL), myelofibrosis, small cell lung cancer and prostate cancer.

Bronce

Genethon

Genethon, created by AFM-Telethon, has the mission to make innovative  gene therapy treatments available to patients affected with rare genetic diseases. To meet this challenge Genethon has assembled the technical and human resources needed to accelerate the medical application of scientific discoveries arising from fundamental research. Strong translational research programs engage multi-disciplinary teams and are supported by a first rate technological platform and cGMP facility

The pipeline of Genethon includes products currently in international clinical trials and at preclinical stages, for muscular dystrophies, immune deficiencies, blood, ocular and liver diseases. These products are developed either with Genethon as sponsor, or in partnership with private companies and academic institutions.

Sigma Aldrich

A reliable, single-source research partner providing high-quality reagents, technologies and industry-leading service to the life science and high technology markets. Scientific knowledge, innovation, high quality products and reliable delivery that support consistent, predictable results and save researchers time, are our strenght. The Company operates in 35 countries and sales in 160 countries whose objective is to provide excellent service worldwide. Global solutions for research and manufacturing customers, with our brands : · Sigma® Life Science : kits and reagents including genomics, functional genomics, proteomics and cell biology. · Aldrich® Chemistry : organic and inorganic chemicals, building blocks, reagents, advanced materials and stable isotopes. · Fluka® Analytical : Chemicals and reagents for analytical, organic and biochemical and pharmaceutical research and industries. · Supelco® Analytical : Chromatography columns and related tools. · SAFC®: Customized services and manufacturing.

TiGenix

TiGenix is a leading European cell therapy company with a commercial product and a strong clinical stage pipeline of adult stem cell programs. The company?s lead product, ChondroCelect®, for cartilage repair in the knee, is the only approved cell-based product in Europe, and is currently being launched across Europe. TiGenix?s adipose derived allogeneic stem cell platform has been extensively validated. TiGenix is based out of Leuven (Belgium) and has operations in Madrid (Spain), and Sittard-Geleen (the Netherlands).

Charles River Laboratories

Every Step of the Way. As a fully integrated partner, Charles River can support your research at any point along the drug discovery continuum.

Esteve


ESTEVE is an international pharmaceutical chemical group that focuses its efforts on innovation and excellence in the field of health, striving daily to achieve customer satisfaction and to contribute to the well-being of society. 
ESTEVE's origins date back to 1929, when Dr. Antoni Esteve i Subirana, researcher and entrepreneur, founded the company with a clear vocation: innovating to live better. Since then, thanks to intensive research, an international approach and an active policy of strategic alliances, ESTEVE has established itself as a leading business group in the area of health.

Histocell

Histocell is a biopharmaceutical company, part of Noray Biosciences Group, for regenerative medicine, developing cell therapy products and novel medical devices for human health. Histocell’s technology is based in the use of adult mesenquimal stem cells (AMSC) applied alone or in combination with new generation biomaterials, which allow to consolidate its position in the development of tissue engineering and advanced therapies drugs

Mafesyster

Mafesyster, empresa suministradora de equipos de investigación, control de calidad y Protección Radiologica . Distribuidora exclusiva y Servicio de Asistencia Técnica Autorizado en España de los Irradiadores biólogicos de animales para investigación marca J.L. Shepherd & Associates de centros de Investigación españoles:

 

CBM (Centro de Biología Molecular de Madrid)   

CNIO(Centro Nacional de Investigaciones Oncológicas de Madrid)

IBM(Centro de investigaciones Biomédicas de Madrid)                  

CIBM(Centro de investigaciones Biomédicas de Granada)

IBIS (Instituto de Biomedicina de Sevilla):

FJC (Fundación Joseph Carreras) – Facultad de medicina de la Universidad de Barcelona

CNIC (Centro Nnal de Invs. Cardiovasculares de Madrid)